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Beilstein J. Org. Chem. 2016, 12, 2784–2792, doi:10.3762/bjoc.12.277
Graphical Abstract
Figure 1: Quinolone signals of Pseudomonas aeruginosa. A) Structures of HHQ and PQS. B) Proposed mechanism fo...
Figure 2: Synthesis of electrophilic ABPP probes. A) Synthesis of α,β-unsaturated amide probes UA1–3. B) Synt...
Figure 3: In vitro labeling of PqsD by chemical probes. A) ABPP probe library with wild-type PqsD and PqsD C1...
Scheme 1: Synthesis of various HHQ and PQS analogues.
Figure 4: Library of HHQ and PQS analogues.
Figure 5: Competitive profiling platform. A) Schematic representation of the competitive labelling strategy w...